Software

Software tools

	ASQ: A proof-of-principle natural language interface to EpiGraphDB that supports the annotation of “claims” in a piece of text (e.g. preprint abstract) with knowledge from the database.
	CScape: A suite of genetic variant effect prediction algorithms for somatic mutations in cancer
	EpiGraphDB: A graph database drawing together a wide array of data types relevant to population health. Access is provided through an API, web application and R package.
	FATHMM: A suite of genetic variant effect prediction algorithms
	LD Hub [RETIRED]: A database of GWAS summary statistics and an analytical platform for LD score regression
	MELODI [RETIRED]: A literature mining platform to identify potential mechanistic pathways between an exposure and outcome
	MELODI-Presto: A rapid API to support programmatic exploration of mechanistic pathways between an exposure and outcome
	MendelVar: A web-based platform to support gene prioritization using data from Mendelian disease genes, variants identified in clinical genetics and data from disease ontologies
	MR-Base: An analytical platform for two-sample Mendelian randomization that utilizes the IEU OpenGWAS database
	MR-KG: A knowledge graph of Mendelian randomization evidence powered by large language models
	OpenGWAS: The IEU GWAS database provides an extensive set of openly accessible genome-wide association study datasets. The IEU OpenGWAS database API provides fast programmatic access to the data. The ieugwaspy package provides a Python interface to the API. A suite of other packages have been developed for this resource within the MRC IEU